What is a key principle of Good Laboratory Practice (GLP)?

A key principle of Good Laboratory Practice (GLP) is the establishment of regulations governing nonclinical laboratory studies. GLP ensures that laboratory studies are carried out consistently, reliably, and ethically, particularly in the context of safety assessments for pharmaceuticals, chemicals, and other products. This framework is essential for ensuring that data generated from nonclinical studies can be trusted, which in turn supports regulatory submissions and decisions about the safety of products.

The application of GLP involves detailed guidelines that laboratories must follow regarding study protocols, quality control, data collection, and record-keeping. By promoting standardization across nonclinical laboratories, GLP helps assure regulatory bodies, researchers, and the public about the integrity and reproducibility of the studies conducted. This is crucial for public health and safety, particularly when products are intended for human consumption or exposure.

Other choices are not aligned with the primary focus of GLP. Conducting studies in a commercial lab may be a setting for GLP but does not define its principles. Ensuring compliance with clinical trial standards pertains more to Good Clinical Practice (GCP), which focuses specifically on research involving human subjects. Improving data management practices, while important for effective laboratory work, is more of a tactic to enhance research quality rather than a defining principle